Which is better - Flebodia 600 or Detralex? Comparison
Varicose veins of the lower extremities are a common pathology that occurs in both men and women. Without treatment, the disease can lead to serious complications that bring not only cosmetic discomfort, but can also cause disability and death.
One of the components of complex therapy is the use of phlebotonics, among which the most effective is Phlebodia 600. In the proposed article, we will examine which Phlebodia analogues are cheaper, but no less effective.
What is the difference between Detralek and Phlebodia?
- is a coated tablet that protects it from destruction by gastric juice. The composition of the medication includes 600 mg of diosmin.
- 500 and 1000 mg coated tablets
- Suspension (fine powder, soluble in water) for oral administration of 1000 mg.
At the same time, the composition of the domestic medicine includes two active components: diosmin (90% of the mass) and hesperidin (10%). Thus, the preparation will have the following dosage:
500 mg tablets contain:
- 450 mg diosmin
- 50 mg of hesperidin,
1000 mg tablets and suspension contain:
- 900 mg of diosmin,
- 100 mg of hesperidin.
Diosmin immediately leads to several positive changes in the vessels:
- Increases the tone of the wall,
- Reduces the formation of inflammation factors,
- Improves the outflow of blood.
Hesperidin acts as an “assistant” for vitamin C, enhancing its beneficial effect. Vitamin C itself stimulates the formation of collagen, the main structural protein in the vascular wall and makes cells more resistant to the harmful effects of inflammatory reactions.
Comparison of indications and contraindications Detralex and Phlebodia
If we compare Detralex with Phlebodia according to indications and contraindications, then what difference between them cannot be found. Both drugs are used for various diseases of the veins, in addition, the composition of Detralex and its foreign counterpart is almost identical.
The drugs are used for:
- Varicose veins of the lower extremities (dilated, protruding and deformed veins on the legs),
- Acute hemorrhoids (expansion of veins around the anus),
- Venous and / or lymphoid insufficiency of the lower extremities (impaired blood outflow with the appearance of edema, pain, a feeling of heaviness and fatigue in the legs).
Contraindications for these medicines also coincide:
- Hypersensitivity (allergy) to the components of the drug,
- Pregnancy and lactation,
- With caution - in patients under 18 years of age.
Comparison of application features
Despite the similar composition, there are differences in the way drugs are used. The course of application of Detralex can be up to 12 months. A day takes 2 tablets (morning and evening), and in acute hemorrhoids - up to 6 tablets per day for a week. Foreign medicine is also drunk in long courses, but, unlike Detralex, only 1 tablet per day, and with hemorrhoids - 2 to 3 tablets per week.
The similarities of the compositions
You can buy medicine in the form of tablets. Venarus, Detralex and Phlebodia contain the same component - diosmin. Detralex and Phlebodia contain another major substance - hesperidin. Both components relate to flavonoids.
The main properties of the drugs: angioprotective, venotonic.
The considered drugs contribute to the expansion of blood vessels, due to which microcirculation is restored in areas where the structure of the walls of the veins is changed. At the same time, the resistance of capillaries to the influence of negative factors increases.Biological fluids pass less intensely through their walls. It is noted that the rheological properties of blood are improved.
Diosmin and hesperidin help eliminate puffiness, because during treatment, venous congestion disappears. At the same time, metabolic processes in cells are normalized. Due to these properties, drugs are used for various vascular pathologies. When using these drugs, the tone of blood vessels rises. This allows you to consolidate the positive result, which was obtained due to the antispasmodic effect of the active components.
Flebodiu is used for various vascular pathologies.
Together with the restoration of vascular function, lymphostasis is eliminated, lymphatic drainage is gradually improving. Diosmin-based preparations can be used to prevent bleeding, for example, simultaneously with the use of an intrauterine device.
A systematic reception of the considered drugs allows to reduce the intensity of negative manifestations with venous insufficiency.
If diosmin and hesperidin are used simultaneously, an antioxidant effect is manifested. This combination inhibits the oxidation of beneficial substances produced naturally, as well as compounds that enter the body through food. This allows you to ensure the saturation of tissues with vitamins, minerals.
Metabolism is normalized at the cellular level. The described processes help to increase the function of blood vessels, because the elasticity of the tissues is restored, the tone is maintained at a sufficient level. As a result, the intensity of negative manifestations in diseases of the veins decreases.
Thanks to the flavonoids contained in the compositions of these drugs, the adhesion of leukocytes to the walls of blood vessels is slowed down. At the same time, the process of their migration to the paravenous walls is inhibited. However, the symptoms of inflammation stop. The considered drugs are used in a number of cases, these are:
- hemorrhoids in different forms,
- venous insufficiency
- the onset of symptoms: leg pain, convulsive contractions in soft tissues, a change in tissue trophism, swelling in the morning and a feeling of heaviness in the evening.
Detralex is recommended for people with venous insufficiency.
Phlebodia is a French drug, due to which the prices for it are slightly higher. It is available only in a dosage of 600 mg per and the prices are distributed approximately as follows:
- Pack of 15 600 mg - 710 r,
- Pack of 18 600 mg - 690 r,
- Pack of 30 600 mg - 1100 r,
- Pack of 60 pcs. 600 mg - 1750 p.
The cost of Detralex looks like this:
- Tablets 500 mg 30 pcs. - 800 r
- Tablets 500 mg 60 pcs. - 1380 r,
- Tablets 1000 mg 18 pcs. - 920 p,
- Tablets 1000 mg 30 pcs. - 1340 r
- Tablets 1000 mg 60 pcs. - 2770 r
- Suspension 1000 mg 15 doses - 820 r,
- Suspension 1000 mg 30 doses - 1590 p.
Which is better - Phlebodia or Detralex?
If you compare what is more effective: the drug Detralex 500 mg or Phlebodia 600 mg, difficulties may arise. Domestic drug is cheaper and it consists of two components that perfectly interact and complement each other. French venotonic is somewhat more expensive and does not contain hesperidin, but its quality, like the quality of other foreign medicines, leaves no doubt. According to experts, Detralex is somewhat more profitable to use: it contains two active substances at once and is cheaper.
If you decide what is best between Detralex at 1000 mg and Phlebodia at 600 mg, then the choice is obvious. The Russian preparation contains more active component, moreover, it contains not only diosmin, but also hesperidin. A slightly higher price is more than compensated by a large dosage, which becomes relevant in the treatment of severe forms of venous diseases (varicose veins, hemorrhoids).
If we consider analogues, then with the identical active substance you can find Venarus, Vazoket, Flebaven.All of these medications can act as a temporary replacement, while for any reason there is no access to Detralex or Phlebodia.
Can I drink at the same time?
Of course, nothing bad will happen if Detralex and Phlebodia are taken together, but there is no point in this. Medicines are similar in composition and are absolutely identical in indications, contraindications, side effects. If the positive effect seems insufficient, then you should try to connect an additional agent to the therapy, for example, an ointment with heparin (dilutes blood), Troxevasin (improves blood flow in small vessels) or something else.
- The medicine does not always help. About half of all patients have a positive effect.
- More often, Detralex helps in the initial stages of the disease,
- If the situation is running, then one drug is not enough in principle,
- Since the course of treatment can last up to a year, the amount of material spent does not always correspond to the effect obtained.
- Compared to Detralex, it helps in about 2/3 of the cases,
- A positive effect develops after a week of administration,
- Even in the late stages of varicose veins, a decrease in the symptoms of diseases can be observed,
- Because of its cost, Phlebodia “hits the wallet” even to wealthy people due to the long course of treatment.
- The drug itself does not have a significant effect. It can only be prescribed as an adjuvant in combination therapy,
- Often patients are scared away by the cost of Detralex and the duration of its admission, because of which they completely refuse treatment,
- Positive results are often visible with instrumental examination of the veins (decrease in intravascular pressure, normalization of blood flow through the deep veins), but they do not appear externally. In the long run, this often saves you from surgery, but “here and now” the patient does not feel any improvement.
- With the right treatment, the effect after the end of the course persists for a long time,
- Side effects rarely develop
- Sometimes it’s hard to convince the patient to take such an expensive drug, but after improvement on the background of treatment, such problems disappear,
- Despite all the effectiveness, the drug should be used as part of a comprehensive treatment.
The phlebotonizing effect of the drugs is directly related to the dose of the drug used. Patients who are interested in: it is better to use Detralex or Phlebodia 600 should familiarize themselves with the recommendations for taking these drugs.
Reception of Phlebodia so that the drug has the necessary therapeutic effect is recommended as follows:
- In order to cure hemorrhoids, the drug can be used up to 3 times a day during the main meal for 1 week.
- In the treatment of vascular diseases of the lower extremities, medication should be taken only 1 time a day, in the morning on an empty stomach.
Detralex is better to use during meals according to this scheme:
- During the treatment of chronic venous insufficiency, 2 tablets per day will be required. The manufacturer indicates that 1 tablet is recommended for use in the daytime, and 2 - during dinner.
- With exacerbation of hemorrhoids, the patient should take 6 tablets per day according to a certain scheme. During the treatment of this disease, it should be remembered when taking Detralex that it is better to combine the use of tablets with drugs for external therapy and diet.
From this we can conclude for people who are interested in: Detralex or phlebodia, which is more convenient for taking varicose veins. For people who value their own time, it is easier to take tablets only once a day and not to distribute the use of the drug throughout the day.
During teratogenicity tests, the preparations showed no adverse effects on the fetus. This makes it possible to use these drugs for pregnant women as prescribed and under the supervision of a doctor. Reception can be carried out from the 2nd trimester of pregnancy.
Comparative characteristics of the composition
Before deciding for yourself: it is better to detralex or phlebodia 600, it is recommended to conduct a comparative description and find out what is the active component of these drugs.
- The composition of the drug Detralex includes 450 mg of diosmin and 50 mg of hesperidin. As additional components, the manufacturer uses microcrystalline cellulose, talc, water, gelatin, and starch.
- The composition of Phlebodia tablets includes 600 mg of diosmin. That is, in this preparation contains a larger amount of active active substance. Auxiliary elements are silicon, cellulose, talc.
When considering the issue, it is better to detralex or phlebodia 600 should take into account the fact that according to the results of angiostereometric studies, both drugs have a positive therapeutic effect on blood flow.
Indications for the use of drugs
In order to accurately determine Detralex or phlebodia, which is better for varicose veins, it is important to know the main indications for the use of drugs.
Both drugs: Detralex phlebodia 600 is widely used in the treatment of the following diseases and conditions:
- Varicose veins.
- Chronic venous insufficiency.
- Symptomatic treatment of lymphatic deficiency, which manifests itself in the form of pain, fatigue and heaviness in the lower extremities, swelling, morning fatigue in the legs.
- Exacerbations of hemorrhoids.
- Detralex and its analogue can be used during the complex treatment of microcirculation disorders.
The drugs have a positive effect on the lymphatic system and this helps to increase the capacity of the capillaries, the expansion of the vascular bed and the elimination of congestion.
Patients who are interested in: better Detralex or phlebodia should take into account the indications for the use of drugs, as well as the needs and characteristics of the body.
Studying information about whether Detralex or phlebodia is better for varicose veins, it should be understood that in this case it all depends on the degree of disease progression. At the initial stage of the development of varicose veins, these drugs will have the proper therapeutic effect: Detralex phlebodia 600. If the disease has reached the 3 or 4 stages of development, then Phlebodia or detralex will be powerless and may require the use of minimally invasive or radical methods of therapy.
Possible side effects and contraindications
Despite its good tolerance, both Phlebodia 600 and Detralex can provoke the development of undesirable side effects. It is known that both drugs can cause development:
- Violations of the gastrointestinal tract in the form of heartburn, nausea, pain in the abdomen.
- In rare cases, the development of allergic reactions in the form of rash, itching, redness, urticaria has been reported.
- It is known that drugs can provoke the development of headache, dizziness and a state of general malaise.
The patient should remember that if, against the background of using the drug Detralex, the development of these or any other side effects is observed, it is necessary to stop taking the tablets and seek medical advice. The most severe side effect is the development of angioedema, which can lead to death.
During the treatment of varicose veins, the doctor may revise the prescribed treatment regimen, reduce the prescribed dosage or choose a drug for replacement.
Both drugs are not used during the treatment of patients with intolerance to the active or excipients of the drug, as well as during lactation.
Both medicines, in spite of what the patient chooses: detralex or phlebodia 600 have the proper therapeutic and prophylactic effect. Patients who have decided what is better to use in the complex treatment of varicose veins can accept recommendations for enhancing the therapeutic effect of a particular drug:
- Patients who take the drug are often interested in: which is better to use at the same time in order to enhance the therapeutic effect. In this case, doctors recommend supplementing the administration of drugs from the group of angioprotectors with medicines for external therapy in the form of creams, ointments, gels.
- It should be remembered when taking Detralex that it is better to additionally use compression knitwear to enhance the therapeutic effect of the drug.
Both drugs cannot be classified as budget ones, however, patients who doubt: what is better - Phlebodia or Detralex should know that both drugs have decent quality. Regardless of what the patient ultimately chooses - Phlebodia or Detralex, both drugs comply with modern European quality standards and have passed all the necessary studies before entering the pharmaceutical market.
What is more effective for varicose veins: Detralex, Venarus or Phlebodia?
The treatment of varicose veins should be aimed at:
- Elimination of the root cause and the provoking factor.
- Strengthening venous vessels and increasing their resistance to adverse factors.
All drugs from the venotonic group can only affect the state of the venous wall, but do not eliminate the cause that led to varicose veins. Thus, Detralex, Venarus and Phlebodia have a similar mechanism of action and one target is the veins. It is possible to draw a conclusion about which remedy better helps with varicose veins after studying the composition or your own experience with these medications.
Venarus or Phlebodia - which is better for varicose veins? Let us compare the preparations according to the main points of the instructions for use, and also capture the Detralex in a review, the analog of which is Venarus.
Venarus comes in pill formcoated. They have an orange-pink color and an oblong shape.
Drug Manufacturer - Russia. Venarus is available in packs with a different number of tablets (20-135 pieces).
The drug belongs to the group of venotonic combined composition. It is dispensed from pharmacies without a prescription.
Detralex is an oval coated tablet. Thanks to the addition of auxiliary components such as iron oxide red and yellow, as well as titanium dioxide, the tablet has an orange-pink color.
Manufacturer - France. Detralex, along with Phlebodia 600, are considered to be original venotonic drugs, by analogy with which most of the others were released. Packs of 30 and 60 tablets are available. The drug refers to over-the-counter leave.
Phlebodia. Film-coated pink tablets. The package contains 30 tablets. The drug is made in France, it is considered high-quality and effective. It is dispensed from pharmacies without a prescription.
Venarus is a combined preparation that contains two active components - 50 mg of hesperidin and 450 mg of diosmin.
Detralex is an original drug with the same combination - 50 mg of hesperidin and 450 mg of diosmin.
Despite the fact that Phlebodia is an analogue of Detralex for varicose veins, this drug contains only one active substance.
Hesperidin is excluded from its composition, and the dosage of diosmin is increased and amounts to 600 mg.In terms of effectiveness, Phlebodia is not inferior to Detralex and is also often prescribed by doctors.
What is better to take with varicose veins - Detralex or Venarus? If the preparations have the same composition, the patient has the right to choose any of them. The decisive points in this case are the price, dosage regimen, manufacturer and quality of the medicine.
To understand the effect of drugs on the body, you need to understand their active substances.
Hesperidin. This is a plant substance.. It belongs to the group of flavonoids.
With regular use, it strengthens the walls of blood vessels and reduces permeability. Due to this, the tone of the veins increases, the severity of varicose veins and the symptoms that bother the patient are reduced.
Hesperidin has a positive effect on microcirculation and lymph drainage.
In addition, the antioxidant effect of hesperidin was revealed, which is very important for the process of updating damaged tissues and blood vessels. Slowing down the process of aging and destruction of cells, hesperidin inhibits the pathological process and enables the body to cope with the problem itself.
Thus, hesperidin has an angioprotective effect, antioxidant and venotonic.
Diosmin also belongs to the group of flavonoids, but is of a semisynthetic origin. Used to treat vein diseases, including hemorrhoidal vasodilation.
Clinical trials have shown that this substance is effective at all stages of the development of venous insufficiency or varicose veins. With regular use of diosmin, the patient's quality of life improves significantly.
Diosmin exhibits a vasoconstrictor effect, the strength of which depends on the dose taken. In addition, the substance reduces stagnation, increases the resistance of capillaries to the action of adverse factors, and reduces their permeability.
Diosmin has a positive effect on lymphatic drainage due to the ability to increase the strength and frequency of contractions of the lymphatic vessels.
In diseases of the veins, which are accompanied by an inflammatory process, an important property of diosmin is the reduction of leukocytes and inflammatory mediators in the focus.
Both substances are rapidly absorbed into the body when taken orally.. The maximum concentration is observed after a few hours, and the largest number is fixed in the deep and saphenous veins of the lower extremities. However, positive clinical dynamics will be observed only after some time, which is necessary to restore the structure of blood vessels and resolve stagnation.
Pharmacological properties and composition of drugs
The drug Phlebodia 600 belongs to the group of medicines that can tone the venous vessels and is prescribed by doctors for varicose veins. The release of Flebodia 600 is in the form of tablets, and the basic component is diosmin. Also in the composition of the tablets there are other components (gelatin, cellulose, etc.).
Detralex is an effective complex drug, since in its composition along with diosmin there is another active component - hesperidin.
This substance helps strengthen the venous walls, reducing pressure and increasing blood flow in the main vessels.
The combination of ingredients such as diosmin and hesperidin increases the tone of the walls of the capillaries, while simultaneously reducing their ability to stretch. Excipients are components similar to Phlebodia.
It is not advisable to use two drugs at once to treat varicose veins. Consultation with a specialist will help you make the right choice.
The main active ingredient in the two drugs is diosmin. The substance has a vasoconstrictor effect on the walls of venous vessels, increasing tone and reducing extensibility and stagnation.
Diosmin increases blood flow in the veins, reducing high blood pressure in patients with varicose veins.
Diosmin also normalizes drainage in the lymphatic vessels, increasing the frequency and intensity of contractions.
Indications for the use of drugs
Both medicines belong to the same group of phlebotonics and have a similar mechanism of action. They are prescribed by doctors to eliminate the symptoms present in chronic venous insufficiency. The main indications for the use of Phlebodia 600 and Detralex are:
- Chronic insufficiency in veins without reverse blood flow,
- Varicose veins of the initial, first and second degree.
In the above cases, it is possible to prescribe monotherapy, which implies the use of only one type of tablet to achieve positive results. If chronic venous insufficiency has complications, Phlebodia 600 and Detralex are used as part of complex therapy, along with anticoagulants and antiplatelet agents.
If vein thrombosis and thrombophlebitis occur, Phlebodia 600 and Detralex will not have a pronounced effect, therefore their use is inappropriate.
Instructions for use
Flebodia 600 and Detralex are taken orally. Detralex tablets are taken for chronic venous insufficiency, 2 pieces per day. The intake of tablets must be divided into two. After 7 days, the scheme changes slightly, now tablets are used once a day in an amount of 2 pieces.
If one of the methods is skipped, an increase in dose is unacceptable. The maximum allowed to use Detralex is 3 months.
The method of application of the Flebodia 600 tablets depends on the type of complications of varicose veins of the legs. For the treatment of venous chronic and lymphovenous insufficiency, it is recommended to take 1 tablet once a day. The course of therapy is up to 2 months. The average severity of varicose veins involves taking tablets for at least 3 months.
With the development of severe venous insufficiency with trophic ulceration, Phlebodia 600 is taken for at least 6 months. Treatment of edema in pregnant women arising from a violation of lymph flow in the lower extremities is carried out by Phlebodia 600, 1 tablet once a day.
A month before the expected birth, the reception of Flebodia 600 is stopped.
Contraindications and side effects
Detralex is contraindicated in patients with hypersensitivity to constituent components. It is not recommended to use Detralex during the period of gestation and lactation. There are no clinical studies regarding the effect on the fetus, but pregnant women should not take the drug.
Also, a medication is able to penetrate into breast milk, so it is not advisable to take Detralex tablets during feeding. The same contraindications apply to Flebodia 600.
For the treatment of varicose veins during pregnancy and lactation, special compression knitwear and external angioprotectors are used.
Side effects with the use of Phlebodia medicinal tablets are rare and do not require special treatment. Perhaps the manifestation of dyspeptic symptoms and migraines.
Reception of Detralex is accompanied by more serious side effects, among which are noted:
- Digestive tract disorders,
- Stool disorder,
- Allergic reactions up to angioedema (Quincke's edema).
Which drug is better
If you compare the tablets Flebodia 600 and Detralex, phlebolg doctors note a higher therapeutic effect of Detralex. But scientists in France have proven that the effect of the tablets is identical. Flebodia 600 differs from Detralex in lower cost and few side effects.
The opinion of experts
Reviews of doctors regarding phlebotonics Detralex and Phlebodia 600 are positive. To increase the therapeutic effect, phlebotonics are used in complex treatment with other types of drugs.
Phlebodia and Detralex are two medications that are priority for the treatment of venous vascular insufficiency due to their high quality and proven therapeutic effect. In addition, both phlebotonics are prescribed not only for treatment, but also for the prevention of varicose veins.
Vladimir Osipovich, Angiosurgeon
More often prescribed drug Detralex, as it is more effective due to two basic constituents. In my practice, there have been no cases of overdose or the occurrence of side effects when taking Detralex.
Igor Antonovich, phlebologist
The drugs are used in combination with creams and compression knitwear.
Patients note the high effectiveness of both Detralex and Phlebodia 600.
I used the drug Detralex as prescribed by my doctor. Was warned of side effects, but nothing happened. I strictly observed the prescribed treatment regimen and really saw the changes for the better. My legs stopped hurting, swelling went away. The result is obvious.
I have long suffered from varicose veins. First, the vascular network appeared, and then other unpleasant consequences of varicose veins - pain, swelling, bulging veins. I went to the doctor, and he prescribed me the drug Flebodia 600. I began to take the prescribed course and saw improvements.
Both drugs have a pronounced therapeutic effect and a preventive effect. To obtain the maximum result, patients are prescribed not only tablets, but also angioprotectors for external use in the form of creams, ointments and gels in the course of varicose veins therapy.
It is also important to remember that in the treatment of varicose veins, it is necessary to use special compression knitwear. This will enhance the therapeutic effect of taking vetotonics.
Neither Flebodia 600, and especially Detralek are not budgetary funds, but the quality of the medicines is excellent, consistent with European standards, and the therapeutic effect has been proven over the years of application and research. However, you should not prescribe yourself treatment for varicose veins. A qualified phlebologist will recommend the right drug and prescribe a treatment regimen.
What is better from varicose veins: Detralex or Phlebodia?
Detralex phlebopratector (analogue - Venorus) is made on the basis of flavonoids (substances derived from plants):
- diosmin - 450 mg,
- hesperidin - 50 mg.
Hesperedin enhances the following medicinal qualities of diosmin:
- normalization of the permeability of the capillary wall,
- improvement of lymph outflow and reduction of swelling,
- decrease in platelet adhesion to the surface of the vascular wall, preventing the formation of blood clots,
- a decrease in the cohesion of white blood cells "stick" to the epithelium inside the vein and a decrease in the inflammatory process,
- has a blood-thinning effect,
- increases the tone of the veins.
Detralex helps to improve blood and lymph flow, prevent the occurrence of thrombosis and eliminate the resulting swelling.
Indications and contraindications for treatment
Detralex helps well with the following diseases:
- chronic venous insufficiency:
- varicose veins I and II degree.
It is approved for the treatment of varicose veins in pregnant women in the 2nd and 3rd trimesters.
There are almost no contraindications. It is forbidden to take only with intolerance to the components of the drug. It is also recommended to drink Detralex for varicose veins if there is no therapeutic effect.
When taking Detrolex, the patient may experience adverse reactions:
- weakness and weakness
- skin rashes,
- intestinal colic
- upset stool.
But negative reactions occur infrequently, most patients tolerate the drug well.
It is recommended to take Detralex on a tablet twice a day with water.The drug begins to act 11 hours after administration, but in order to feel the effectiveness of the therapy for varicose veins, it is necessary to drink Detralex for 3 months.
The cost of the drug is from 650 p. per pack of 30 capsules.
Unlike Detralex, Phlebodia 600 has fewer negative effects. When taking the medication, you may see:
- nausea (sometimes vomiting)
- abdominal pain,
- diarrhea or constipation.
Adverse reactions in the treatment of Phlebodia 600 occur more often than with Detralex.
Phlebodia 600 is excreted from the body for a long time and 1 capsule per day is enough to maintain the therapeutic concentration of the drug for varicose veins, and the course of treatment is 2 months.
The price of Flebodia 600 is 750-850 r for 30 tablets.
Pros of Flebodia 600
Compared with Detralex, the use of Flebodia 600 with varicose veins has several advantages:
- Ease of use. The active substance is excreted from the body for a long time, so it is enough to drink Phlebodia 600 per tablet per day,
- A shorter course of treatment. To achieve a stable therapeutic effect with varicose veins, Flebodia 600 drink 2 months, and Detralex - 3 months,
- Less adverse reactions. Phlebodia 600 does not cause skin rashes and does not provoke the appearance of edema.
It seems that Phlebodia 600 has an advantage over Detralex in the treatment of varicose veins, but hasty conclusions should not be drawn. Before choosing, let's get acquainted with the advantages of Detralex.
Pros of Detralex
Phlebodia 600 “wins” compared to Detralex in cure rate and convenience, but Detralex has a number of advantages:
- Use during pregnancy. Detrolex is allowed to be used in the 2nd and 3rd trimesters for the treatment of varicose veins in expectant mothers. There is no safety data for the fetus when prescribed for varicose veins Flebodia 600, so doctors do not recommend drinking medication to ladies in an interesting position,
- Rare side effects. Despite the fact that Phlebodia 600 causes fewer negative reactions than Detrolex, they occur more often. Detralex is better tolerated by patients.
Well, one should not forget that Detralex is a complex drug and, in addition to diosmin, contains hesperidin. In addition to enhancing the therapeutic effect of diosmin, hesperidin helps to reduce the inflammatory process, improves cellular metabolism and has an antioxidant effect.
A bit about saving issues
Despite the fact that the doctor prescribes the medicine for varicose veins, the majority, wanting to save money, are asked to prescribe instead of Phlebolia 600 to drink Detralex for varicose veins.
These medicines are not structural analogues and, if there are no particular contraindications, you can replace one medicine with another without harming the treatment of varicose veins.
But, before insisting on replacing the medication, consider what is more profitable.
- Price per pack. Flebodia 600 costs 750-850 p. per pack, while the price of Detralex will be from 650 p.,
- Multiplicity of reception. With varicose veins, Detralex should be drunk twice a day, and Flebodia 600 - once. That is, a pack of Flebodia 600 is enough for a month, and Detralex packaging for 15 days and will have to purchase a new one. Already more expenses
- Treatment duration. To achieve a sustainable therapeutic effect with varicose veins Flebolia 600 you need to drink 2 months, and Detralex - 3.
In financial terms, treating varicose veins with Phlebodia 600 is beneficial, but the choice depends not only on the cheapness of the drug, but also on many other factors.
What affects the choice of drug
Before choosing what to use for the treatment of varicose veins: Phlebodia 600 or Detralex, the doctor takes into account the following:
- Allergic history. With a tendency to allergic reactions, Detralex is better to use for varicose veins than Phlebodia,
- Tolerance of active substances. If the patient has heresperedin intolerance, but there is no allergy to diosmin, then with varricosis, Phlebodia 600 is prescribed,
- The presence of pregnancy (in women). Varicosis during childbearing often occurs, and doctors consider Detralex safer than the relatively new drug Flebodia 600. Most manufacturers indicate pregnancy and lactation in the contraindications section of Flebodia 600.
- The severity of edema. Despite the fact that the drugs are equally effective for varicose veins, taking Detrolex can provoke an increase in swelling. In this case, prefer Flebodia 600,
- Gastrointestinal diseases. Diosmin irritates the mucous membrane of the digestive tract and, with diseases of the stomach or intestines, dyspeptic disorders may occur. A single dose of Detralex contains less diasmin, which means less irritation of the mucous membranes occurs. For diseases of the digestive system, the use of Phlebodia 600 is undesirable,
- The price issue. If the patient tolerates both medicines well, then the choice is made in favor of a more convenient and cheaper Phlebodia 600,
With advanced forms of varicose veins, the patient is prescribed to take Detralex and Flebodia 600 together.
At the same time, taking Phlebodia increases the daily dose of diosmin and slows its elimination from the body, and hesperidin enhances the therapeutic effect of the active component.
The interaction of drugs helps to quickly get rid of heaviness in the legs, reduce swelling and reduce the size of the resulting venous nodes.
From the comparative characteristics, we can conclude that Phlebodia 600 is more effective, but do not immediately rush and ask to replace the prescribed Detralex with this drug. When prescribing a medicine for varicose veins, phlebologists take into account not only the condition of the veins, but also other data on the patient's condition:
- test results,
- health status,
- tendency to allergic reactions,
- state of the digestive system.
Based on the results of the examination, a medication is selected to increase venous tone and eliminate intravascular inflammation, but not harm the stomach or other organs.
But one should take into account the fact that some doctors prefer to prescribe such familiar and proven drugs as Detrolex from varicose veins, being wary of new drugs. Do not self-medicate, independently changing one medication to another, you should not, but you need to ask about the possibility of replacing drugs.
Which is better is hard to say. Despite the fact that Phlebodia 600 “wins” as a more effective and financially beneficial remedy for varicose veins, in some cases, it will be better for the patient to conduct Detralex therapy.
Therefore, if you prescribed Detralex, and a friend or relative drank Flebodia 600, you do not need to self-medicate and run to the pharmacy on the recommendation of a person far from medicine. The best cure for varicose veins for the patient is selected individually.
According to reviews and articles of periodical medical publications, Flebodia 600 and Detralex are prescribed for varicose veins more often than other means and are ahead of their analogues. These include, for example, Venarus, which is also part of the venotonic group and has positive characteristics in the treatment of varicose veins.
At the initial stages of the development of the disease, Detralex and Flebodia 600 significantly slow down its progression, allowing the immune system to better cope with malaise.
With proper treatment and compliance with the recommendations of doctors, both drugs can stop negative trends and allow the patient to feel much better.
At later stages of varicose veins, the drug is taken in order to eliminate pronounced symptoms.
In addition, any drug that belongs to the category of venotonics has a positive effect in preventive measures and reduces the risk of relapse and complications.
They also help in preparing the patient for surgery, which is prescribed in especially severe cases, because
with the right combination with the other elements of complex therapy, they increase the positive effect of treatment, reducing the likelihood of negative consequences of surgical intervention.
The effect of drugs on the body
Detralex is based on diosmin and hesperidin, which are:
- Tonify the vessels, allowing them to function better.
- Increase the elasticity and strength of the venous walls.
- Stabilize blood supply.
- Eliminate pain on the skin and its pathological sensitivity.
- They reduce the permeability of capillaries and increase their stability (i.e., the drug does not cause dependence).
- They make vascular resistance better, normalize blood pressure (especially in the postoperative period).
- Contribute to the effectiveness of lymphatic drainage.
- Reduce stagnation in the blood channels and eliminate the difficulties of blood outflow arising from varicose veins.
A qualitative feature that allows the body to absorb Detralex better than other analogues is associated primarily with the unique processing technology of its constituent substances.
Phlebodia 600 also contains diosmin, but in a higher percentage. Thanks to this, Phlebodia stimulates the lymph nodes much better. Due to this, the elimination of stagnant phenomena, this drug carries out more productively than its analogues. Based on this, it is especially recommended to take it to persons with a diagnosis of combined lymphovenous insufficiency.
Appointments and contraindications
Detralex is usually prescribed in courses. Depending on the symptoms, the duration of treatment may vary. However, the average course of therapy is from 2 to 3 months (up to 2 times a year). With varicose veins, Detralex should be taken no more than 2 times a day.
In case of hemorrhoids, in case of acute pains, the medicine, on the recommendation of doctors, is best taken in the amount of 3 capsules: once during the day and once in the evening. Such a course, as a rule, takes no more than 4 days. Further, the drug is used for another 3 days in the amount of 2 capsules twice a day.
The peculiarity of Detralex's intake is that it is used strictly with food. The course of treatment for chronic hemorrhoids is at least 3 months.
With varicose veins, Flebodia 600 is prescribed in the same courses, but the dosage is calculated in one capsule during the day. With hemorrhoids, Phlebodia should be taken 2 tablets 2 times a day, then 1 tablet per day.
The negative consequences of using Detralex with varicose veins are rarely recorded. Do not talk about this and patient reviews. Among the side effects, the researchers called violations of the stable functioning of the digestive tract and complex autonomic disorders.
Nausea and persistent discomfort may be observed.
Detralex is usually prescribed in courses.
The main contraindications to the use of Detralex are called:
- The period of feeding the baby.
- Intolerance to active substances (diosmin and hesperidin).
The peculiarity of this medicine, which its analogues cannot boast of, is that during many years of experiments aimed at studying its effect, the researchers were not able to identify absolutely any negative effects on the fetus. Therefore, with varicose veins or hemorrhoids, it is Detralex that is best suited for women who are pregnant.
Adverse reactions of Phlebodia 600 include headache, nausea, rarely - allergic manifestations and individual intolerance.
Flebodia 600 capsules are contraindicated:
- In the first trimester of pregnancy.
- In the period of active lactation.
- To minors.
In addition, the use of Phlebodia 600 for the treatment of varicose veins or hemorrhoids is not recommended for people who are hypersensitive to a number of medications.
The cost of medicines and opinions about them
The price of Flebodia 600 is extremely unstable and varies in the range from 540 to 1030 rubles. Detralex also distinguishes the same, the price of which varies between 681 and 1484 rubles. However, it is not possible to compare drugs by this parameter because of the difference in the number of capsules taken.
Reviews for these analogues also differ not much. Both drugs have a high price as negative qualities. In general, for 10 positive reviews, each drug has 1 negative. Approximately every 20th author claims that neither one nor the other drug led to any results.
Based on the reviews, Flebodia 600 very effectively helps with varicose veins, eliminates stagnation of lymph. A positive effect begins to be observed in the second week of therapy. Fixed a decrease in swelling of the veins.
Often, the authors, in addition to describing the standard positive dynamics during the treatment of Flebodia 600, talk about improving the emotional background, stabilizing mood, etc.
Among the epithets awarded to the medicine, the words “effective” are most often found.
A positive effect begins to be observed in the second week of therapy.
Detralex deserves positive characteristics in patients for lifting legs. Based on many reviews, this tool copes better with ankle lymphostasis. Effective removal of edema and even a strong analgesic effect are noted.
However, after the abolition of treatment, the pain in the legs begins to gradually return and again captures the patient in the second month. Some patients report increased stamina in the legs.
In addition, one of the main advantages of this drug is that it can be consumed during pregnancy.
The described analogues are very effective and are actively used for:
- Varicose veins.
- Chronic venous insufficiency.
- Swollen veins in the lower extremities.
- Feeling of heaviness in the legs.
- The development of hemorrhoids (especially with acute pain).
Both Flebodia 600 and Detralex are perfect not only for treatment, but also for the prevention of vein diseases and are prescribed for burning, diagnosed microcirculation disorders, as well as for increased fragility of capillaries.
Therefore, it is not possible to make an unambiguous conclusion about which drug is better.
The only thing that can be done to choose this or that means is to study in detail the positive and negative qualities of each, in order to choose the characteristics that are most suitable for themselves.
So, Detralex and Flebodia 600 are almost similar in composition. Their only fundamental difference is that the latter does not contain such a substance as hesperidin, and the amount of diosmin in its composition reaches 600 mg.
This difference gives rise to different modes of capsule administration. Many patients as a positive side of Flebodia 600 noted just a single dose during the day.
However, others note the negative fact that it should not be consumed during pregnancy.
Both Flebodia 600 and Detralex are perfect not only for treatment, but also for the prevention of vein diseases.
The mechanism by which the analogs of Phlebodia and Detralex act on the patient's body is almost identical.
The special technology by which the substances that make up Detralex are processed provides it with additional positive quality - it is absorbed better and faster by the body.
And that means it has a faster healing effect. Phlebodia 600, in turn, better stimulates lymphatic drainage.
The list of contraindications for Flebodia 600 is wider and more serious, which is primarily due to the higher content of the active substance that this drug contains in its composition. The main limitation in the use of phlebodia is pregnancy.
When choosing one or another drug, it is worth remembering that what is the individual reaction of each individual organism to the combination of medications in the structure of the drug is of great importance.
The same substance can have a fundamentally different effect on two specific patients. Moreover, its effectiveness as a medicine will have a different degree of severity.
In conclusion, it should be recalled that in the prescription of medicines for varicose veins, as with any other disease, an individual approach to each patient is necessary. Drug therapy is prescribed only by a phlebologist. And often to conclude which particular drug is best for a particular patient is possible only by careful selection.
Features of the drug
Phlebodia 600 is a drug belonging to the group of venotonics and angioprotectors.
Available in the form of tablets, it is prescribed for varicose veins of the lower extremities, lymphovenous insufficiency, impaired blood flow in the veins of the legs, concomitant diabetes.
After administration, the active substances from the tablets enter the bloodstream and are evenly distributed along the walls of the hollow and saphenous veins. The drug acts pointwise, improving blood circulation in the vessels of the lower extremities and pelvic organs.
The effect on the liver, kidneys, stomach and other organs is insignificant. Residues of active substances are completely eliminated from the body within 12 hours.
Since the main cause of varicose veins or its varieties, hemorrhoids, is a violation of the structure and tone of the venous wall, it is recommended to correct pathological changes with drugs that restore the elasticity of the veins. Such a pharmacological group includes systemic and local venotonics (phlebotonics), angioprotectors.
The active ingredient in drugs that are used to treat varicose veins (and its special case - hemorrhoids) are different components. The most effective are diosmin and its combination with hesperidin. These are flavonoids - the largest class of plant polyphenols that give antioxidant activity to drugs, tannins, are natural dyes.
The most popular representatives of this category of medicines are the two French drugs Detralex and Flebodia 600. In fact, these are diosmin-based analogues that are necessarily included in the regimen for the treatment of varicose veins or hemorrhoidal disease. So what is better: Phlebodia or Detralex? Is there a fundamental difference?
The Russian analogue of Phlebodia, whose average cost is 678-1543 rubles.
Phlebof is produced in tablets that contain 600 mg of the active substance. The drug is not inferior in quality to foreign analogues.
Phlebof is contraindicated in pregnant and lactating women, as well as children under 18 years of age. Medication rarely causes side effects such as nausea and headache.
A higher dosage of diosmin helps to accelerate recovery in case of impaired vascular function. However, good results are also obtained during therapy with preparations containing a combination of 2 active components. These include Venarus, Detralex. The drugs in question differ in the form of release. Flebodia 600 and Venarus are produced only in tablet form.
Detralex can be purchased in the form of tablets and oral suspension.
The preparations differ in the type of components. Venarus contains 450 mg of diosmin and 50 mg of hesperidin. In the same amount, the active substances are part of Detralex.Phlebodia is different in that it contains only diosmin at a concentration of 600 mg.
In addition, of all the funds examined, only Venarus is available in tablets that are protected by a shell. Due to this, the release of active components in the stomach will slow down. As a result, more beneficial substances are absorbed into the tissue of the mucous membranes, because they are destroyed more slowly.
Which is better - Venarus, Detralex or Phlebodia
Each of the tools provides a sufficient level of effectiveness. They differ in similar compositions, therefore, exhibit the same properties. Hesperidin and diosmin are substances that belong to the group of flavonoids. The mechanism of their action is similar, therefore, when combining these components, an increase in the effectiveness of the drug is noted.
Venarus contains hesperidin and diosmin, which increase the effectiveness of the drug in the treatment of blood vessels.
Venarus and Detralex contain 500 mg of flavonoid fractions. For comparison, Phlebodia contains 600 mg of diosmin. This flavonoid performs the same functions as the components used in combination in the composition of Venarus and Detralex. Given that diosmin is contained in a larger dosage, it acts more efficiently. However, with a combination of 2 types of flavonoid fractions, the antioxidant effect is more pronounced.
So, in terms of effectiveness, all funds are on the same level. For each of the patients, the best is the drug that does not provoke the development of side effects. For this reason, if you are prone to allergies, you should check how the single-component medicine Phlebodia and the combination of diosmin, hesperidin will affect the body.
Among venotonic drugs produced by Russian manufacturers, the following drugs are most effective and affordable:
In addition to diosmin, venotonic agents may include substances such as rutin and troxerutin. By pharmacological effect, they are similar to preparations containing other flavanoids.
Can I take at the same time
Given that all products contain the same component - diosmin, it is impractical to use them simultaneously. This will increase the daily dosage. If you want to change the treatment regimen with one of the drugs because of its low effectiveness, it is enough to increase the amount of the chosen agent. This will enhance the therapeutic effect.
If you use the drugs at the same time (Venarus, Detralex, Flebodia), the daily dose will be 3200 mg (taking into account the fact that 2 tablets per day should be taken according to the scheme).
Long-term therapy according to this scheme can cause the appearance of negative symptoms, which is due to the ability of diosmin and hesperidin to affect the properties of blood and the state of vascular tissue.
Contraindications when using Venarus, Detralex and Phlebodia
These drugs are not used in some cases:
- with the development of negative hypersensitivity reactions to any component in the composition,
- during lactation, because there is no information about whether the active components get into mother’s milk,
- for children under 18 years old.
During pregnancy, Venarus and Detralex can be used if the intended benefit exceeds the possible harm. However, phlebodia is not used in the 1st trimester. Such limitations are due to the fact that this drug contains more diosmin.
Side effects from Venarus, Detralex and Phlebodia
During therapy with Venarus and Detralex, negative reactions occur:
- violation of the stool
- general weakness
- muscle cramps
- inflammatory process in the intestines,
- violation of the respiratory system: chest pain, sore throat,
- allergy in this case can manifest as dermatitis, urticaria, angioedema.
Phlebodia contributes to a hypersensitivity reaction, dyspeptic disorder (heartburn, nausea, abdominal pain).There is no information on cases of overdose in excess of the recommended amount of funds. However, with a significant change in the treatment regimen, there is a risk of enhancing the listed side effects.
How to use
The course of treatment is selected in accordance with the type of disease and the type of drug. For example, Venarus and Detralex are used in the same way, due to the identity of the compositions:
- for most vascular diseases: 2 tablets per day, with the first dose taken in the afternoon, the second in the evening,
- with hemorrhoids during the exacerbation period: 6 tablets per day, and the medicine is taken in the morning, the second dose in the evening, after 4 days the daily amount of the drug is reduced to 4 tablets, the duration of administration at this stage of therapy is 3 days.
Phlebodia is taken according to another scheme. The recommended daily dose is 1 tablet per day. Take the drug preferably in the morning. If acute hemorrhoids develop, the daily amount of the drug increases to 2-3 tablets. The duration of the course is 1 week.
Analogs on iHerb
It is worth noting that in addition to the retail pharmacy chain, phlebotonics can also be found on the Internet. The famous iHerb website offers the widest selection of environmentally friendly dietary supplements based on herbal ingredients.
Means containing diosmin, which can be ordered on iherb, are presented in the following list:
- Life Time, Diosmin and Hesperidin complex (60 capsules) - 693.77 rubles,
- Life Extension, European foot remedy based on the certified Diosmin complex (30 capsules) - 831.63 rubles,
- Doctor’s Best, Best Vein Support (60 caps) - 899.68 rub,
- Jarrow Formulas, Venous Optimizer (90 tabs) - Rs 1,020.56,
- Natural Factors, WomenSense, VeinSense, support for veins (60 caps) - 1099.20 rub.
When choosing dietary supplements to replace official medicines, you need to consult a doctor. It is worth remembering that this group of drugs does not pass all stages of pharmacological control and is not a drug.
With varicose veins
According to the mechanism of action, the drugs are similar, therefore, with such a disease, Venarus, Phlebodia or Detralex can be used. It is important to consider the body's response to therapy.
So, Phlebodia provokes fewer side effects, this drug is more convenient for treatment, since only 1 tablet is enough to take per day.
The advantage of Venarus and Detralex is the combination of diosmin and hesperidin, which helps to slow down the oxidation of beneficial compounds, which is also important for varicose veins, because due to this, the metabolism is gradually restored and the state of the vessel walls is normalized.
What can replace system venotonic
As mentioned above, effective treatment of varicose veins is possible only with an integrated approach. At the same time, ointments and gels with a phlebotonic effect have a positive effect not only on the vascular wall, but also on the condition of the skin.
The most effective topical agents are:
- Troxerutin (36-51rub).
- Venoruton (279-366rub).
- Troxevasinum (128-174 rubles).
- Herbion Exulus (97-122rub).
- Venitan (RUB 145-255).
Ointments, gels and creams are applied in a thin layer on the affected skin in the morning and evening. The simultaneous use of these products with elastic stockings or a bandage that is worn after completely absorbing the soft dosage form is effective.
Phlebodia provokes fewer side effects. This tool acts less aggressively on the intestines, which is important for hemorrhoids. In addition, the drug contains a substantial dose of diosmin, and this allows you to accelerate recovery. Detralex and Venarus provoke a violation of the stool, inflammatory processes in the intestines. In this case, the condition of the tissues with hemorrhoids in the acute period may worsen.
Pharmacy Vacation Terms
All the funds considered belong to the group of OTC drugs.
Detralex, Venarus - these drugs can be purchased at a price in the range of 700-1600 rubles. Phlebodia is found at a higher cost - up to 1900 rubles. The difference in price is due to the difference in the dosage of active ingredients, the form of release of drugs.
Scope of application
Phlebodia, Detralex and Venarus are used for diseases in which there is a violation of the outflow of venous blood. These drugs can be prescribed for:
- Venous insufficiency.
- Varicose veins.
In addition, venotonics can be prescribed by doctors as a prophylactic to prevent the above problems. As a rule, pregnant women, athletes, smokers, people with hard physical work become patients and risk groups in this case.
The selection criterion for the patient between analogues is often the convenience of administration. Detralex and Venarus are used in the same way. They are prescribed 2 tablets per day, which are divided into two doses and drunk at regular intervals.
Thus, it is possible to achieve a stable concentration of active substances in the blood and constant maintenance of the therapeutic effect. Tablets are taken with meals, without chewing and drinking with plain water.
According to clinical studies on the drug Flebodia 600, it was enough to use 1 tablet per day in the treatment of venous insufficiency. If necessary, the doctor can increase the daily dose, but 1 tablet is the optimal amount. After a month of treatment, the patient's condition improves significantly. With continued therapy, the structure of the venous vessels and their functions are restored.
Preparations from the venotonic group are intended for long-term use, and most of them are allowed to be used during pregnancy. All this indicates a high safety profile of drugs and a low likelihood of overdose. The official instructions for Venarus, Phlebodia and Detralex saythat cases of overdose with these drugs are unknown.
Patient reviews about what is better with varicose veins - Detralex or Venarus are different. Despite the same composition, people choose one of the means according to other parameters or personal preference. Some of the differences between these drugs are listed below.
|Composition||Two active substances||Two active substances||One main component|
|Multiplicity of admission per day||Twice||Twice||1 time|
|Price for 30 tablets||800 p.||500 p.||900 p.|
Moreover, the pharmacological effects of these drugs are approximately the same. Among them are:
- Phlebotonic effect - increases the tone of the veins, reduces their extensibility, enhances resistance to adverse factors.
- Lymphatic drainage - increases the frequency of contraction of the lymphatic capillaries, their tone and functional density.
- Microcirculation improvement, resorption of stasis, a decrease in the permeability of capillaries.
- Decrease in production and transfer mediators of inflammation in the affected area, a decrease in the adhesion of leukocytes, blocking the production of free radicals.
- Improving oxygen intake to tissues and accelerate the regeneration process.
Which drug to choose?
According to clinical trials, Phlebodia and Detralex showed approximately the same results and are considered equivalent analogues.
To the question "what is better with varicose veins - Detralex or Phlebodia?" Doctors' reviews are distributed equally. At the same time, preference is given to drugs of French quality, rather than to Russian Venarus.
On the part of patients, on the contrary, Venarus is chosen quite often. The reason, as a rule, is that Venarus has a composition similar to Detralex, but at a more affordable price.Each patient must make the final decision on his own, focusing on the criteria that are most important to him - quality, price, regimen, reviews of other people.
With regular and long-term use, all venotonics help to eliminate unpleasant symptoms. These drugs can be drunk and preventive courses twice a year.. However, the pharmacological effectiveness of drugs must be supported by a proper diet, active lifestyle, and other methods.
A very good additional tool for the prevention and even the fight against varicose veins is compression underwear. In more detail about stockings from varicose veins for pregnant women, as well as women's compression underwear for sports with varicose veins, we talked about in these articles.
In some cases, the problem of varicose veins is complicated by the localization of the disease or the inability of the patient to change jobs. This includes movers, truckers, varicose veins during pregnancy, which manifests itself in the groin, and not on the legs.
Notice any changes in your body. Remember that the first symptoms of varicose veins are small spider veins and a feeling of fatigue in the legs. The sooner treatment begins, the more effective the result.
The effectiveness of the tablets Flebodia 600 with hemorrhoids
The drug is used for external, internal or combined hemorrhoids. Tablets are especially effective in the initial and middle stages.
With timely admission, they prevent the formation of hemorrhoidal nodes, condense the vascular walls, preventing their damage. Treatment should be carried out under the supervision of a doctor, he will select the optimal dosage and supplement the therapeutic regimen with other necessary medicines.
Phlebodia tablets are capable of:
- strengthen venous walls, improve their elasticity,
- prevent the formation of hemorrhoids,
- improve lymph outflow by removing internal and external edema,
- prevent internal microcracks,
- regulate blood flow, preventing venous stasis.
Composition and packaging
Flebodia 600 is produced by a large French pharmaceutical company. The drug in the form of pinkish-red coated tablets is packaged with transparent blister cells of 15 pieces.
Blisters are packed in cardboard boxes of 1-2 pieces and supplied with instructions. The medicine is sold over the counter.
The main active substance that is part of the tablets is diosmin. It has a pronounced venotonic and anti-inflammatory effect, improves oxygen supply to tissues, and prevents the activity of free radicals.
As auxiliary components are present: talc, stearic acid, silicon dioxide, microcellulose.
The tablets are rapidly absorbed, the therapeutic effect lasts up to 96 hours. The remains of the drug are excreted in the urine without accumulating in the kidneys or liver. Shelf life of the product is 3 years, after the end of this period, tablets cannot be used. Keep them in a cool, dark place, away from children and pets.
With exacerbation of hemorrhoids, it is recommended to take 2-3 tablets per day before meals.
The course lasts 10 days, if necessary, you can continue.
In chronic hemorrhoids, Phlebodia take 1-2 tablets for 20 days.
The approximate scheme, the exact dosage and time of administration are prescribed by the attending physician.
Detralex and phlebodia 600: what is better and what is the difference (difference in formulations, reviews of doctors)
Many patients complain that they have problems that lie in varicose veins of the lower extremities.
Such a process is often accompanied by swelling and heaviness in the legs, swelling and a feeling of fullness of the veins, pain. To get rid of unpleasant symptoms, doctors prescribe venotonic agents.
Therefore, there are often doubts about which drug is better to take: Detralex or Phlebodia 600.
Detralex and Phlebodia 600 are venotonic agents.
Features of use
Flavonoid-based drugs are taken orally. Despite the identity of the indications and contraindications, there are still features of the use of each drug.
The venotonic effect of the active substances is directly dependent on the dose used. This is the first nuance that gives an answer to the question about the advantage of a particular tool.
The optimal effect of taking phlebodia with hemorrhoids, you need to drink tablets with meals three times / day for a week. For the treatment of varicose veins of the lower extremities, a single dose of the drug in the morning, on an empty stomach, is enough. The course of therapy is up to 2 months. With moderate varicose veins - at least 3 months, with severe venous insufficiency with trophic ulceration - at least 6 months.
Detralex is effective with a different dosage regimen. Chronic venous insufficiency involves the use of the drug in the morning and in the evening: a tablet with meals. Hemorrhoids require six tablets / day in combination with external therapy and diet.
If one of the methods is skipped, an increase in dose is unacceptable. The maximum allowed use of a complex of flavonoids is 3 months.
In other words, phlebodia looks more convenient to use because of the concentration of the active substance.
As for teratogenicity, the chances of drugs are equal: both are safe, applicable from the second trimester.
What is better with varicose veins?
Most clearly, the advantages and disadvantages are visible in the table:
|There is an additional flavonoid hesperidin, enhancing the action of diosmin and leveling the difference in the concentration of the base||The concentration of the active substance exceeds Detralex, which allows you to take the drug once|
|There is a dosage of 1000 mg, where diosmin is 900 mg and hesperidin is 100||It has fewer side effects (drug instructions)|
|More allergic||Expensive drug|
|Requires multiple admission / day|
The drug is sold in tablet form. Designed for indoor use. There are two types of medicine - Detralex 1000 and Detralex 500. The tablets are oval and have a pinkish tinge. Top coated with a film sheath.
As active substances are:
- diosmin - 450 or 900 mg,
- hesperidin - 50 or 100 mg.
In 1 contour cell there are 15 tablets. In 1 cardboard package 2 or 4 blisters are placed.
It is a venoprotective and venostabilizing drug. It is considered a corrector of blood microcirculation.
It is prescribed for acute and chronic hemorrhoids. Helps with severity, swelling and pain in the legs.
The cheapest substitutes
|Name||The country of manufacture||Package price 30 caps||Package price 60 caps|
A comparison of the cost of Detralex, produced in France or Russia, and the French drug of the same company, Phlebodia, immediately makes the patient pay attention to the fact that a tablet of diosmin with hesperidin is almost half the price than monodiosmin.
However, it is worth considering the duration of the course of therapy in order to understand what is more affordable in terms of price. Detralex tablets will require twice as much remission (or a larger dosage, which is more expensive) to achieve remission. And now, let's calculate: about 1000 rubles will have to be paid for a pack of Flebodia in 30 tablets. This is a monthly course, with complicated varicose veins or hemorrhoids, the duration of treatment may increase depending on the effect obtained.
The cost of packing Detralex of 60 tablets is about 1,500 rubles. This is also a monthly course, the duration of which can increase. Obviously, buying Detralex is more expensive.And most importantly, proctologists are sure that the pharmacological effectiveness of the drugs is comparable and does not give any particular benefits to any of the drugs.
30 years ago in France they decided to make a complete comparison of the effectiveness of the combination of flavonoids diosmin (450 mg) and hesperidin (160 mg) with a dosage of monodiosmin of 600 mg. For this, two groups of volunteers were selected. The first took Phlebodia 600 once, the second - twice - Detralex.
We got the following: the results of the action of the drugs were no different from each other, since the mechanism of action of the main components was almost identical. The final result is presented in the table.
|Mechanism of action||Same||Same|
|Dose||Double reception||Single dose|
|Side effects||More pronounced||Less pronounced|
|Price||1,500 per month course||1,000 - per month rate|
Thus, it turns out that the Flebodia 600 has some advantages in terms of price and side effects. At the same time, we must not forget that in the early stages of hemorrhoids or varicose veins, the complex composition of the Detralex drug wins according to the results of therapy: the combination of two flavonoids has a more powerful and lasting effect, prevents relapses.
Therefore, when choosing one or another remedy for the treatment of venous insufficiency, the advice of a doctor is required, which will take into account the accurate diagnosis, individual characteristics of the patient and tolerance of the components of the drugs.
Characteristic Flebodia 600
Medication can be purchased in pill form. They have a biconvex shape and are covered with a pink shell. The composition includes diosmin. Its content in 1 tablet is 600 mg.
In the blister is 15 pcs. The total amount is 30 and 60 tablets.
The action of the drug is aimed at reducing the extensibility of the veins, strengthening the capillary walls, getting rid of stagnation of blood in the veins. The active substance affects the lymphatic vessels, thereby lowering the pressure in them and expanding the density of the vascular bed.
The action of the drug is aimed at reducing the extensibility of the veins, strengthening the capillary walls, getting rid of stagnation of blood in the veins.
Side effects of Detralex and Phlebodia 600
In most cases, medicines are well tolerated by patients. Side symptoms are rarely observed in the form of:
- nausea, pain in the upper abdomen, an unpleasant odor from the oral cavity,
- headaches and dizziness,
- rashes on the skin, itching and redness.
With increased susceptibility to diosmin, anaphylactic shock or Quincke edema develops.
If adverse reactions are weak, then they pass on their own. In other cases, symptomatic therapy is required.
Which is better - Detralex or Flebodia 600
Diosmin is considered one of the best substances for combating varicose veins. Phlebodia contains 600 mg of the active ingredient. If there is no therapeutic effect, then Detralex should be preferred, because it includes a combination of diosmin and hesperidin.
This drug is often included in complex therapy for diseases of bones and joints in the form of arthrosis.
If you compare prices, the Flebodia 600 is the cheaper analogue. For 30 tablets, you will have to pay 700-800 rubles. Detralex is more expensive. The minimum cost is 890 rubles.
per dosage of 500 mg.
Flebodia 600 or Detralex: which is better for varicose veins, comparison, components, which is more effective
Varicose veins are a fairly common venous pathology, especially among the elderly. It is very important at the first signs of a violation of the state of the vessels to take measures to restore their health.
Since without proper blood circulation in the body, which ensures a healthy circulatory system, there can be no question of the full existence of the human body.
With the restoration and maintenance of tone, elasticity and elasticity of the vascular system, drugs called angioprotectors are excellent at it. They will be discussed in this article. Let's look at Flebodia 600 (Flebodia 600) or Detralex - which is better with varicose veins?
The mechanism of action of Phlebodia 600 and Detralex
Angioprotective drugs, such as Detralex and Flebodia 600, are designed to restore and protect the healthy functioning of arterial, venous, capillary vessels and to improve blood circulation through them. The effect of angioprotectors is aimed at inhibiting hyaluronidase, anti-bradykinin activity, and inhibition of prostaglandin biosynthesis. Detralex and Flebodia 600 are similar in composition, and therefore the principle of influence on the body.
Pharmacological action of angioprotectors Phlebodia 600 and Detralex:
- Activation of metabolic processes in blood vessels, due to which the elasticity of blood vessels of the blood system is completely regenerated and their resistance is established.
- Improving the rheological properties of blood, that is, its "fluidity". Improving blood flow contributes to: a decrease in platelet coagulability, an increase in the elasticity of red blood cells, a decrease in the viscosity of the blood substance.
- The restoration of microcirculation of blood flow in the vessels of the spine, due to which the metabolism of blood flow with tissues is significantly improved.
- Normalization of vascular tone is achieved due to the antispasmodic activity of angioprotectors Flebodia 600 and Detralex. With increased tone, the vessels expand, thereby reducing the tension of the vascular walls. And with a reduced tone, under the influence of capillaroprotective drugs, narrowing of the vessels is achieved to increase the voltage of the walls.
Varicose disorders have a tendency to progression, which as a result leads to irreversible changes in the vessels, in the later stages that can only be resolved surgically. Angioprotectors such as Flebodia 600 and Detralex have proven themselves in the clinical practice of treating vascular pathologies.
Thanks to phleboprotectors, doctors manage to significantly reduce the percentage of cases of complications of varicose pathologies.
But patients often have a fair question as to whether the use of Flebodia 600 or Detralex is better for varicose veins. The answer to this question can really be obtained only if you thoroughly examine both angioprotectors and compare the clinical characteristics of the drug Detralex and Flebodia 600.
Pharmacological properties of Detralex
Detralex exerts an effect on the circulatory system due to bioflavonoids, plant components of natural origin found in berries, fruits and vegetables. Namely, diosmin, which in the tablet of the drug contains 450 mg and hesperidin in a quantitative value of 50 milligrams.
Diosmin in combination with hesperidin helps to reduce intralymphatic pressure and reduce the diameter of the lymphatic capillaries. Detralex's uniqueness lies in the technology of processing these substances, which is called micronization. Thanks to this technical process, fast and complete absorption of the active components of the angioprotector is carried out.
Pathologies in which Detralex is prescribed:
- Varicose veins, including its very initial stage, which is expressed as the appearance of vascular networks on the body, often on the lower extremities.
- Chronic venous insufficiency (CVI), accompanied by a sensation of pain and heaviness of the legs.
- Hemorrhoidal pathology.
Detralex is effective for varicose vessels of the first and second degrees. And when the venous insufficiency proceeding in the chronic stage does not have such a complication as a reverse blood flow (reflux), due to the inferiority of the venous valve.If reflux occurs, then Detralex is prescribed in combination therapy with drugs of a different principle of action.
In this case, anticoagulants, antiplatelet agents, and other necessary drugs are usually added to the treatment of varicose veins.
The regimen for taking Detralex is very simple - it is taken only 2 times a day through equal periods of time with meals. The course of therapy with this tool is from two to three months. To achieve maximum effect, the drug cycle can be repeated. But conducting a three-month therapy is not recommended more often than two full courses per year.
- Improving vascular tone.
- Reducing venous extensibility.
- Strengthen the walls of arteries, veins, capillaries.
- Normalization of microcirculation of blood flow.
- Reducing stagnant processes in the vascular system.
- Restore drainage and outflow of lymph.
Side effects in the treatment of Detralex are very rare, this is due to the possibility of its long-term use. But nevertheless, minor neuralgic disorders are possible, expressed as dizziness or malaise.
Sometimes mild dyspeptic disorders are observed, such as heaviness in the stomach, rapid satiety, a feeling of overflow, stool disturbance, nausea, heartburn.
Also, in exceptional cases, individual intolerance to Detralex may occur, which is easy to suspect if a skin rash or itching appears.
Pharmaceutical Specifications Flebodia 600
The drug Phlebodia 600, as its name implies, contains 600 milligrams of the tablet of the main active ingredient of micronized diosmin. As an additional substance in an amount of 900 mg, microcrystalline cellulose is in a tablet of Flebodia 600.
This component additionally has a positive effect on the vessels in the form of improving their patency by eliminating excessive cholesterol, as well as lowering blood sugar.
Exposure to Flebodia 600:
- Bringing vessels in a healthy tone.
- Elimination of stagnant processes in the vessels.
- Improving capillary resistance.
- Regulation of tissue blood supply.
- Blocking the synthesis of prostaglandins and thromboxane.
- Anti-inflammatory effect.
- Restoration of lymphatic drainage and venous outflow.
Based on the properties, the drug Flebodia 600 is prescribed if:
- Disrupted capillary circulation.
- Varicose veins are present.
- There is lymphatic venous insufficiency of the legs.
- Hemorrhoidal pathological changes were revealed.
Due to the natural components of Flebodia 600, the drug does not have side effects.
It is allowed to be used even during pregnancy (required after consultation with a doctor), only not recommended during lactation.
Phlebodia 600 angioprotector, like its Detralex analogue, is contraindicated mainly only in case of individual intolerance to the components of the drug. Detralex and Flebodia should not be applied to 600 persons under the age of majority.
Flebodia 600 is used according to the standard regimen once in the morning before the first meal. But depending on the venous pathology, the dosage of the angioprotector is increased. The same applies to the duration of use of Flebodia 600, the duration of administration to achieve a therapeutic effect starts from two and can reach up to six months.
How to supplement treatment
Phlebodiv tablets are venotonic, they strengthen the vascular walls and relieve swelling. However, the drug does not affect the development of inflammation, is not able to relieve severe pain, burning and itching. Other drugs can solve these problems.
For pain relief ointments and rectal suppositories with novocaine, lidocaine and other anesthetics. It is possible to take oral drugs: antispasmodics, anticonvulsants, lung antidepressants.
Small damage can be cured. external compresses, bactericidal gels or suppositories with antibiotics.
Diosmin, which is part of the tablets, enhances the effect of certain drugs, for example, adrenaline. This must be taken into account when drawing up a therapeutic regimen. For greater effectiveness, it is worth including vitamins A, E and C, as well as zinc and magnesium, in the treatment program.
Comparative analysis of Detralex and Flebodia 600 with choledol
Name of drug Positive facts Negative aspects
|Detralex||One tablet of Detralex contains hesperidin, which enhances and expands the clinical effect of diosmin.||Detralex has more side effects than Phlebodia 600.|
|Phlebodia 600||In combination with diosmin, the Flebodia 600 preparation contains microcrystalline cellulose, which contributes to an additional positive effect on the vessels and the whole body. |
In the Flebodia 600 preparation, dioxin is contained in a large dosage, which in untreated cases allows you to manage with just one tablet per day.
|Phlebodia 600 has a higher cost compared to Detrolex.|
|Choledol||Absolutely natural! The main active substance is amaranth seeds and juice. The plant contains squalene, a component that effectively lowers cholesterol. Its effectiveness is confirmed by research by the Research Institute of Therapy and Preventive Medicine. The composition of choledol also includes: blueberry fruit juice, clover flowers, native garlic concentrate, stone oil, wild garlic juice. All components of the product effectively lower cholesterol and restore all body systems.||It will be more expensive than Flebodia 600 and Detralex, if bought in pharmacies, and not on the manufacturer's website here.|
So, we can summarize that both drugs both Phlebodia 600 and Detralex have a good therapeutic effect in the treatment of vascular pathologies, we recommend natural choledol.
Ideally, the alternation of Detralex and Phlebodia 600 agioprotectors can be recommended for a full-scale positive effect on the circulatory system.
But the main condition for choosing Detralex or Phlebodia 600 is still the individual tolerance of auxiliary components, in addition to dioxin.
Analogues of the drug
Detralex is considered a complete analogue of Phlebodia. Both drugs are available from major French pharmaceutical companies and are sold over-the-counter.
Medicines are interchangeable, they can be used in one therapeutic regimen.
The only difference is the pill regimen. Detralex requires a more complex schedule, with exacerbation of hemorrhoids, it is recommended to take up to 6 tablets. It is advisable to combine the drug with ointments and suppositories, which has a hemostatic, antitumor and venotonic effect. A sparing diet and proper drinking regime are required.
Some experts believe that Phlebodia is more effective, as it contains more diosmin. However, Detralex has a milder effect on the intestines, side effects are less common. The final choice depends on the patient's condition.
Another drug from the venotonic group is Venarus.
Russian-made tablets are cheaper than French counterparts, and in terms of effectiveness are practically comparable to them.
The drug contains diosmin and hesperidin, it locally affects the veins of the pelvic area and has virtually no contraindications.
For the treatment of the initial stage of hemorrhoids, another one is suitable domestic drug - Venozol. It contains diosmin, horse chestnut and hazelnut extract.
The medicine acts very gently and is suitable for patients who have an allergic reaction to hesperidin. Venozol is available in the form of tablets, capsules and ointments; to enhance the effect, it is recommended to combine external and oral preparations.
Phlebodia 600 is a drug that has repeatedly proved its effectiveness.It has been successfully used to treat various forms of hemorrhoids, showing the best results at the initial stage of the disease. Tablets fit well into any therapeutic regimen, have a minimum of contraindications, and very rarely cause side effects.
Which is better: Phlebodia 600 or Detralex?
In order to compare the preparations, it is necessary to pay attention to the main characteristics: form of release, indications, contraindications, method of use, pharmacokinetics, side effects.
Initially, the French drug Detralex appeared on the Russian market. It is available in tablet form, 500 mg. active ingredient, diosmin. Additionally, the active substance of hesperidin is included. In view of the high cost, Russian pharmacology decided to manufacture a drug, Venarus, which has a similar composition.
It is recommended to use both drugs with:
- Acute hemorrhoids to relieve symptoms,
- Prevention of thrombosis, thrombophlebitis,
- Pain, severity, swelling in the legs, accompanying varicose veins,
- Damage to blood vessels, veins,
- Venous insufficiency.
Venus, like Detralex, has an angioprotective, venotonic, anti-inflammatory effect. Both drugs help tone the walls of blood vessels, improve lymph flow and blood flow, correct microcirculation, reduce fragility and extensibility of the capillary network.
During treatment, Venarus or Detralex will have to stop breastfeeding. No studies have been conducted regarding the effect on the child of the first medication. Detralex showed that the drug is able to penetrate and remain for some time in the mother’s milk, which negatively affects the development of the baby.
Among the adverse reactions there are nausea, psychological discomfort, pain in the digestive tract. A lot of reviews suggesting a negative effect of Venarus on the digestive system in patients with concomitant chronic gastritis, duodenitis, or other gastrointestinal diseases.
Venus or Detralx tablets will be used in the morning, in the evening according to the doctor’s testimony. The pharmacokinetics of both drugs is similar - the period of complete elimination is about 11 hours. The dosage is calculated individually by the doctor. As well as a course of treatment. On average, it is 2 months intermittently, it is recommended to drink 1 tablet in the morning with meals.
Comparing Venus and Detralex, we can conclude:
- The drugs have various producer countries (France, Russia),
- A more effective and faster positive reaction occurs (according to patients' reviews) during treatment with Detralex,
- Taking pills for varicose veins is prescribed in the morning and according to the testimony of a specialist in the evening,
- The dosage during the treatment of varicose veins is standard for both drugs - 1 to 2 tablets per day,
- General composition, list of contraindications, indications for use,
- The same period of excretion from the body,
- Drugs should not be drunk while breastfeeding,
- Various studies have been conducted on Detralex tablets, and their effectiveness has been proven, unlike Venarus.
The price of tablets will also differ, which sometimes plays a significant role in the selection. Detralex, the average cost of which varies from 600 rubles to 2500 depending on the number of tablets in a package, exceeds the price of Venarus 2 times (450-1500 rubles).
Since the course of treatment for varicose veins is at least 2-3 months, the cost of Detralex can significantly hit the patient’s pocket, so often he decides in favor of the Russian counterpart.
Vnenarus or Flebodia 600
It is necessary to compare Phlebodia 600 and Venarus, both medicines can be used in the treatment of varicose veins of the legs. Unlike the previous pair of drugs, the data are not direct analogues, they are included in the same pharmacological group of venotonics.
To understand which drug is better, Venarus or Flebodia 600, you should consider in more detail the characteristics of the last medication.
|The country of manufacture||France|
|Composition||Diosmin, 600 mg. (more than Detralex and Venarus).|
|Release Forms||Tablets, in a package of 15, 30, 60 pieces.|
|Indications for use|
|Contraindications||Tablets can not be used during pregnancy up to 12 weeks, with natural feeding, under the age of 18 years, in the presence of an allergic reaction to the drug.|
|Adverse reactions||Occur rarely in the form of headaches, disturbances in the digestive tract.|
|Withdrawal Period||A little over 11 hours.|
|How to take medicine||Take 1 tablet (unless otherwise prescribed by a doctor), before breakfast. The average course of treatment is 2 months.|
Phlebodia 600 in the treatment of varicose veins helps:
- Improve venous blood flow,
- Relieve swelling, inflammation, pain and heaviness in the legs,
- Reduce the stretching of the walls of blood vessels and improve their tone,
- Improve microcirculation at the capillary level,
- Strengthen the effects of adrenaline and norepinephrine,
- Improve lymph drainage,
- Increase tissue oxygen supply.
Flebodia 600 has a price slightly higher than Venarus (600-1800 rubles). Tablets do not have hesperidin in the composition, but have an increased level of diosmin, which affects effectiveness. The effect of taking Phlebodia 600 according to doctors, is higher.
Pharmacological properties of Phlebodia 600
The medicine Flebodia 600 is a medication that can lead to a state of vein tone, it is prescribed by doctors for varicose veins. Available in the form of tablets, the basis is diosmin. Additional components are gelatin and cellulose.
In addition to diosmin, Detralex also has hesperidines, which acts as an equally effective component. It helps strengthen the walls of blood vessels, reduce pressure and improve blood flow. With the interaction of these two components, the effect of reducing the stretching of blood vessels is achieved. Additional elements are identical to Phlebodia 600.
Diosmin is the main active ingredient and performs the function of strengthening blood vessels. It can begin to be taken at any stage of the development of the disease. It has the ability to renew the venous walls and restore the metabolism necessary for the body. During oral administration, the medicine is quickly absorbed and begins to fulfill its functions.
Flebodia 600 is recommended to be taken throughout the course, but the first positive signs are monitored on the second day.
Positive results from taking the drug:
- Increased tone in the vessels and veins.
- Improving lymphatic drainage.
- Reducing inflammatory processes.
- Puffiness subsides.
- Painful manifestations are reduced.
Latest Information: Preparations for the treatment of leg vessels: the best pills and injections
The drug is prescribed at all stages of the disease: with venous insufficiency and various pathological changes in the vessels. The main indications for taking Phlebodia 600 are varicose veins of the legs, interruptions in the processes of blood microcirculation and hemorrhoids. The medicine is prescribed for admission, both in a single copy, and in combination with other medicines.
Despite the undeniable positive effect of the reception, there are a number of cases in which the reception is contraindicated, these are:
- individual intolerance to the main or additional components,
- the patient's age is less than 18 years,
In addition, the use of the drug during breastfeeding is not recommended.
Reception and side effects of Phlebodia 600
The medicine Flebodia 600 can be prescribed only to adult patients.
The drug is prescribed by the attending physician taking into account individual characteristics and the results of the examination of the patient's body. In accordance with the instructions for use, with varicose veins, in order to eliminate the symptoms of the disease, 1 tablet is prescribed 1 time per day.
According to the recommendations, the most favorable time for admission is on an empty stomach before breakfast. The course of treatment in this case will be at least 60 days.